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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PLCH2 All Species: 11.21
Human Site: S982 Identified Species: 24.67
UniProt: O75038 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O75038 NP_055453.2 1416 154668 S982 P A Q E G P G S G S P R D T R
Chimpanzee Pan troglodytes XP_001149239 1685 188441 V961 R S L Q A R P V S M P V D R N
Rhesus Macaque Macaca mulatta XP_001085424 1423 155915 S989 P A Q E G P G S G S P R D T R
Dog Lupus familis XP_546733 1387 151432 S966 S A P E E P G S R S P R D T R
Cat Felis silvestris
Mouse Mus musculus A2AP18 1501 164279 S1063 P T Q E R S G S S S P R D T R
Rat Rattus norvegicus Q62688 1096 122754 V695 Q N G G C G Y V L R P S I M R
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q2VRL0 637 72514 K236 S V I H V V D K Y A F A A S D
Frog Xenopus laevis Q32NH8 758 87399 K357 H G R T F T S K I L F K D V I
Zebra Danio Brachydanio rerio A5D6R3 784 89362 F383 T L T S K V L F K E V I E T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P25455 1318 146373 K917 V Q V G G Q K K E L R P V E S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783611 2724 302530 E1202 K L E H Y D P E P A P T L S R
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 46.4 94 78.7 N.A. 77.2 21.2 N.A. N.A. 21.2 24.7 24.5 N.A. 24.2 N.A. N.A. 26.4
Protein Similarity: 100 59.9 95.4 82.9 N.A. 81.6 36.7 N.A. N.A. 30.7 35.3 35 N.A. 40.3 N.A. N.A. 35.7
P-Site Identity: 100 13.3 100 73.3 N.A. 73.3 13.3 N.A. N.A. 0 6.6 6.6 N.A. 6.6 N.A. N.A. 13.3
P-Site Similarity: 100 26.6 100 73.3 N.A. 73.3 13.3 N.A. N.A. 13.3 20 13.3 N.A. 6.6 N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 28 0 0 10 0 0 0 0 19 0 10 10 0 0 % A
% Cys: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 10 0 0 0 0 0 55 0 10 % D
% Glu: 0 0 10 37 10 0 0 10 10 10 0 0 10 10 0 % E
% Phe: 0 0 0 0 10 0 0 10 0 0 19 0 0 0 0 % F
% Gly: 0 10 10 19 28 10 37 0 19 0 0 0 0 0 0 % G
% His: 10 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 10 10 0 19 % I
% Lys: 10 0 0 0 10 0 10 28 10 0 0 10 0 0 0 % K
% Leu: 0 19 10 0 0 0 10 0 10 19 0 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % M
% Asn: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 28 0 10 0 0 28 19 0 10 0 64 10 0 0 0 % P
% Gln: 10 10 28 10 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 10 0 10 0 10 10 0 0 10 10 10 37 0 10 55 % R
% Ser: 19 10 0 10 0 10 10 37 19 37 0 10 0 19 10 % S
% Thr: 10 10 10 10 0 10 0 0 0 0 0 10 0 46 0 % T
% Val: 10 10 10 0 10 19 0 19 0 0 10 10 10 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 10 0 10 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _